The historic town centre of Alì is divided into two sides of different date, the older of presumed Arab origin, the newer one going back to the late-1500s. 

The Chiesa Madre dedicated to St. Agatha is the main and most attractive religious building. Its imposing interior has a basilical plan with monolithic columns and a transept with cupola. It is ornamented with several works of art such as a wooden choirstall graced by panels depicting scenes from St. Agatha’s life.